Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons
نویسندگان
چکیده
منابع مشابه
Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons
Brain-derived neurotrophic factor (BDNF) plays an important role in hippocampus-dependent learning and memory. Canonically, this has been ascribed to an enhancing effect on neuronal excitability and synaptic plasticity in the CA1 region. However, it is the pyramidal neurons in the subiculum that form the primary efferent pathways conveying hippocampal information to other areas of the brain, an...
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متن کاملAction of brain-derived neurotrophic factor on function and morphology of visual cortical neurons
Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2016
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00186.2016